Evaluation of Serum Apelin-13 in Psoriasis Vulgaris Patients

Document Type : Original Research Papers

Authors

1 Dermatology, Venereology and Andrology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

2 Clinical Pathology and Immunology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

Abstract

Psoriasis is a chronic, T-cell mediated inflammatory skin disease with multifactorial etiology. Recent studies support the relation of psoriasis with obesity. Apelin-13 is a novel adipokine that is secreted from white adipose tissue and plays a role in T-cell immunity. In this study, it was aimed to investigate potential relationship between apelin-13 and psoriasis. Serum apelin-13 was measured in 60 patients with moderate to severe psoriasis vulgaris and 30 healthy controls using enzyme-linked immunosorbent assay (ELISA). Serum levels for apelin13 clinched alongside patients with psoriasis vulgaris might have been discovered on make higher over On solid controls (P

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