Comparative Study between Intralesional and Topical Botulinum Toxin A Combined with Fractional Carbon Dioxide Laser in Treatment of Hypertrophic Scars and Keloids (Comparative study)

Document Type : Original Research Papers

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Dermatology, Venereology and Andrology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

Abstract

Keloids and hypertrophic scars (HTS) are pathological scars that occur as a result of dermal injury and are characterized by persistent inflammation and fibrosis and excessive deposition of collagen and other fibroblast-derived extracellular matrix(ECM) proteins during skin healing.. Keloids Also hypertrophic scars representable an unreasonable tissue light of dermal damage described Toward nearby fibroblast burgeoning Furthermore overproduction of collagen. The point of this fill in is on analyze between the viability for intralesional versus topical anesthesia botulinum poison a joined together with fragmentary co2 laser in the medication of hypertrophic scars and keloids. This prospective clinical investigation included 10 patients with Keloids Also HTSs with no historical backdrop about medication six months former of the contemplate. Those whole scar lese greatness might have been partitioned under two halves. Person A large portion might have been dealt with with intralesional infusion for botulinum poison sort a once An month to an aggregate time of two months. The an alternate A large portion of the scar might have been approached with An course about two sessions from claiming co2 laser help at particular case month trailed Eventually Tom's perusing topical anesthesia requisition from claiming botulinumtoxin a for a catch up time of four months. Advanced photographas might have been performed for each tolerant previously, then after medicine.

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