Significance of Neutrophil/Lymphocyte Ratio with Coronary Artery Calcium Score Detected by Multislice Computed Tomography as A Predictive Marker of Ischemia in Type 2 Diabetes Mellitus Patient

Document Type : Original Research Papers

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Cardiology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

Abstract

Neutrophil-to-lymphocyte ratio (NLR) is an inexpensive, easy to obtain, widely available marker of inflammation. T2DM and inflammatory markers including NLR were shown to have impact on coronary artery disease (CAD) or carotid artery atherosclerosis. to examine the affiliation and essentialness of Neutrophil/Lymphocyte Ratio (NLR) with Coronary Artery Calcium Score (CACS) and Obstructive Coronary Artery Disease (CAD) identified by Multislice Computed Tomography (MSCT) Angiography in Type 2 Diabetes Mellitus (T2DM) patients. This examination included one hundred sort 2 diabetic patients, who are either asymptomatic or suggestive (yet non-trademark) for coronary corridor illness (CAD) and experienced MSCT angiography. All the included cases were exposed to research facility examination including investigation of (CBC, liver and kidney work tests and lipid profile). Electrocardiogram and echocardiography were done to evaluate the cardiovascular capacity and recognize any indications of intense coronary condition and myocardial localized necrosis. Multi-cut registered tomography picture reproduction and CAD assessment report was acquired to all the cases. The mean age of the cases was 54.56±8.39 years, with mean span of DM was 8.16±6.07years. There were 71males(71%) and 29 females(29%) ,52 cases were hypertensive (52%) , 52 cases were smokers(52%), 69 cases didn't have family ancestry of untimely coronary vein disease(69 %) while 31 cases had family ancestry of CAD(31%). CACS uncovered higher affectability (77.4% with AUC 0.691) at cut off 16 ounces 105 as contrasted and NLR (75.5% with AUC 0.639) at cut off point 1.95 in forecast of obstructive IHD.

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