Glaucoma Diagnostic Accuracy of Ganglion Cell Inner Plexiform Layer Thickness Comparison with Peripapillary Retinal Nerve Fiber Layer

Document Type : Original Research Papers

Authors

Ophthalmology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

Abstract

Glaucoma is an optic neuropathy characterized by progressive loss of retinal ganglion cells (RGCs) and their axons, eventually resulting in visual field loss. As glaucomatous visual misfortune is irreversible, early determination is significant; be that as it may, this can be trying because of enormous between singular variety in ordinary plate appearance, between onlooker contrasts in circle assessment, and absence of affectability of visual field testing because of physiological excess in retinal ganglion cell responsive fields. The reason for this investigation is to decide the symptomatic exhibition of macular ganglion cell–internal plexiform layer (GCIPL) thickness and to contrast it and that of peripapillary retinal nerve fiber layer (RNFL) thickness to segregate typical eyes and eyes with early glaucoma. 20 eyes with early glaucoma (case gathering) and 20 ordinary eyes (control gathering) were joined up with this examination and their RNFL and GCIPL boundaries were estimated utilizing Topcon 3D ghostly space OCT 2000. the GCIPL and RNFL were more slender and the vertical cup-to-circle width proportion was bigger in subjects with glaucoma than in typical subjects. What's more, aggregate and sub-par GCIPL values were the most exact for the analysis of early glaucoma. high hazard gathering and analyzed gathering of glaucoma ought to be catch up with RNFL and GCIPL thickness utilizing OCT.

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