Troponin I Biomarker for Cardiac Affection in Patients with Androgentic Aloepcia

Document Type : Original Research Papers

Authors

Dermatology,Venerology and Andrology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

Abstract

The plasma level of two common cardiovascular disease markers, cardiac troponin I and C-reactive protein, in alopecia areata and AGA affected subjects. We aimed to assesment of troponin I level of patients with AGA to detect if there is arole of troponin I as a cardiac biomarker for cardiac affection in the disease (AGA) pathogenesis and it's associations and looking for a hidden cardiac problem. The study was conducted on 75 participants; 50 patients suffering from Androgenetic alopecia, in addition to 25 control normal healthy persons. Norwood Classification for male Pattern Baldness Ludwig Classification of Female Pattern Baldness , ECG, Determination of serum Cardiac troponin I and Echocardiography were done for all participants. troponin I showed significant positive correlation with age, GLS, grades, as well as significant negative correlation with EF troponin I showed significant positive correlation with age, GLS, grades, as well as significant negative correlation with EF.