Comparison between Induction of Ovulation with Clomiphene Citrate with or without Withdrawal Bleeding in Patients with Polycystic Ovary Syndrome

Document Type : Original Research Papers

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Obstetrics , Gynecology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

Abstract

Polycystic ovary condition (PCOS) is a typical heritable and heterogeneous issue described by ovulatory brokenness with hyperandrogenic status, notwithstanding the polycystic morphology of the ovaries. Treatment of anovulation begins with weight decrease in fat ladies, through to careful control of the ovaries. A few medicines been utilized for acceptance of ovulation. This investigation expected to assess the impact of clomiphene citrate in enlistment of ovulation in patients with polycystic ovarian syndrome(PCOs) without prompting withdrawal seeping in examination with the conventional convention of clomiphene citrate. Techniques: complete of 60 barren ladies matured 20 – 40 years of age with the conclusion of PCOS , who introduced to Benha University Hospital at the barrenness outpatient facility , were enrolled for the investigation , all patients were arbitrarily isolated into two gathering :Group 1 (study gathering ): Group II (Control gathering ): Transvaginal ultrasound folliculometry was done 5 – 7 days after finish of CC treatment . Results: This examination had indicated that the all out number of follicles, mean follicular width and endometrial thickness after incitement was altogether more when beginning CC in (luteal stage) than (follicular phase).Conclusion:Early organization of CC in late luteal stage (before withdrawal shedding) in patients with PCOS may prompt more follicular development, ovulatory patients and endometrial thickness which may ponder higher pregnancy rate than organization of CC in early follicular stage (from second day to fifth day of cycle).

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