Abo Elazm, T., Ismail, Y., Ebaid, H., Darwish, M., Taha, M. (2021). Chemerin as a Biomarker of Acute Coronary Syndrome. Benha Journal of Applied Sciences, 6(1), 279-284. doi: 10.21608/bjas.2021.169127
T.H. Abo Elazm; Y.M. Ismail; H.H. Ebaid; M.S. Darwish; M.M. Taha. "Chemerin as a Biomarker of Acute Coronary Syndrome". Benha Journal of Applied Sciences, 6, 1, 2021, 279-284. doi: 10.21608/bjas.2021.169127
Abo Elazm, T., Ismail, Y., Ebaid, H., Darwish, M., Taha, M. (2021). 'Chemerin as a Biomarker of Acute Coronary Syndrome', Benha Journal of Applied Sciences, 6(1), pp. 279-284. doi: 10.21608/bjas.2021.169127
Abo Elazm, T., Ismail, Y., Ebaid, H., Darwish, M., Taha, M. Chemerin as a Biomarker of Acute Coronary Syndrome. Benha Journal of Applied Sciences, 2021; 6(1): 279-284. doi: 10.21608/bjas.2021.169127
Chemerin as a Biomarker of Acute Coronary Syndrome
1Cardiology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt
2Clinical,Chemical Pathology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt
Abstract
Intense coronary disorder (ACS) is a condition (set of signs and indications) because of diminished blood stream in the coronary courses with the end goal that piece of the heart muscle can't work appropriately or kicks the bucket. The point of study is to assess chemerin levels in patients with intense coronary disorder. The investigation included 100 subjects who were ordered into two gatherings; control bunch which included 20 subjects with typical coronary discoveries, and cases bunch which included 80 cases with ACS (counting STEMI, NSTEMI, and UA). All cases and controls were exposed to finish history taking, careful actual assessment, and routine lab examinations. Likewise, serum chemerin were estimated for all cases and controls. The mean age of the included subjects was 55.99 and 56.2 years for ACS and control bunches individually. Guys spoke to 55 and 52.5% of cases in the two gatherings individually, with no measurably huge distinction between the two gatherings (p=0.448). Serum chemerin level was fundamentally higher in the ACS gathering (268.8 ng/ml versus 115 ng/ml in controls – p < 0.001). On separating ACS cases into 3 subtypes, there was mellow huge distinction between STEMI, NSTEMI, and UA (p = 0.086). The best cutoff purpose of Chemerin to foresee the event of ACS was >249.5 ng/ml with 74.6% affectability, 82% particularity, 78% PPV, 72% NPV and precision of 72%. Chemerin was more touchy than troponin in distinguishing cases with ACS.
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