Salama, K., Sakr, B., Azab, S. (2021). Short Letrozole Therapy Versus Extended (Long) Letrozole Therapy For Induction of Ovulation in Women With Polycystic Ovary Syndrome. Randomised study. Benha Journal of Applied Sciences, 6(2), 243-253. doi: 10.21608/bjas.2021.169459
K.M. Salama; B.E. Sakr; S.A. Azab. "Short Letrozole Therapy Versus Extended (Long) Letrozole Therapy For Induction of Ovulation in Women With Polycystic Ovary Syndrome. Randomised study". Benha Journal of Applied Sciences, 6, 2, 2021, 243-253. doi: 10.21608/bjas.2021.169459
Salama, K., Sakr, B., Azab, S. (2021). 'Short Letrozole Therapy Versus Extended (Long) Letrozole Therapy For Induction of Ovulation in Women With Polycystic Ovary Syndrome. Randomised study', Benha Journal of Applied Sciences, 6(2), pp. 243-253. doi: 10.21608/bjas.2021.169459
Salama, K., Sakr, B., Azab, S. Short Letrozole Therapy Versus Extended (Long) Letrozole Therapy For Induction of Ovulation in Women With Polycystic Ovary Syndrome. Randomised study. Benha Journal of Applied Sciences, 2021; 6(2): 243-253. doi: 10.21608/bjas.2021.169459
Short Letrozole Therapy Versus Extended (Long) Letrozole Therapy For Induction of Ovulation in Women With Polycystic Ovary Syndrome. Randomised study
Obstetrics and gynecology, Dept.,Faculty of Medicine, Benha Univ., Benha, Egypt
Abstract
Presentation: Polycystic Ovary Syndrome is quite possibly the most well-known reasons for anovulatory fruitlessness, influencing 8-13% of conceptive matured ladies . It is by a long shot the most well-known reason for hyperandrogenic anovulatory fruitlessness and was depicted the greater part a century prior, the basic reason for this issue is as yet dubious . Point: to examine the viability of short(2.5mg day by day for 5 days) versus broadened course (2.5mg day by day for 10 days) of letrozole treatment for ovulation acceptance in ladies with polycystic ovary syndrome.Subject &Method: This examination directed on (40) patients with PCOS They were arbitrarily assigned in two gatherings. Gathering 1 (20 patients )got letrozole in adose of 5mg for 5 days while the gathering 2 (20 patients) got letrozole in adose of 2.5 mg for 10 days.Result : The all out number of follicles in the present moment letrozole was 3±1 while it was 4±1 in the long letrozole bunch. In our examination the endometrial thickness was 8±2 in both short and long letrozole bunch .The pregnancy rate was 15% in short letrozole bunch while it was 25% in long letrozole bunch . End: The long letrozole treatment (2.5mg for 10 days) can create more develop follicles and in this manner a greater number of pregnancies than the short letrozole treatment (5mg for 5 days).