Ibrahim, A., Ibrahim, S., Abd Allatif, W., Shahin, S. (2021). Assessment of Serum Level of VASPIN in Acne Patients. Benha Journal of Applied Sciences, 6(4), 157-161. doi: 10.21608/bjas.2021.189902
A.A. Ibrahim; S.E. Ibrahim; W. Abd Allatif; S.M. Shahin. "Assessment of Serum Level of VASPIN in Acne Patients". Benha Journal of Applied Sciences, 6, 4, 2021, 157-161. doi: 10.21608/bjas.2021.189902
Ibrahim, A., Ibrahim, S., Abd Allatif, W., Shahin, S. (2021). 'Assessment of Serum Level of VASPIN in Acne Patients', Benha Journal of Applied Sciences, 6(4), pp. 157-161. doi: 10.21608/bjas.2021.189902
Ibrahim, A., Ibrahim, S., Abd Allatif, W., Shahin, S. Assessment of Serum Level of VASPIN in Acne Patients. Benha Journal of Applied Sciences, 2021; 6(4): 157-161. doi: 10.21608/bjas.2021.189902
Assessment of Serum Level of VASPIN in Acne Patients
1Dermatology and Andrology, Dept., Faculty of Medicine, Benha Univ., Benha, Egypt
2Clinical pathology, Dept., Faculty of Medicine, Benha Univ., Benha, Egypt
Abstract
Background: Acne vulgaris is a prevalent chronic skin condition with pilosebaceous blockages and/or inflammation (hair follicles and their accompanying sebaceous gland). Aim: to investigate vaspin levels in serum of acne sufferers in comparison with normal controls and to link their levels with the severity of the illness. Methods: 30 instances of AV and 31 healthy control groups have been examined and each patient has been submitted to comprehensive history; complete clinical examination and levels of serum vaspine were calculated. Methods: Results: The level of vaspin was much greater in the AV group than the control group (medium=2785.2 vs 155.4 against p < 0.001). For discriminating between AV patients and control groups, the Vaspin level receiver operating characteristic curve (ROC) has been performed. Vaspin exhibited o.989 AUC. At a cut-off of 212.2, sensitivity was 96.7%, the specificity of 96.8%, 96.7%, NPV was 96.7% and the accuracy of 96.8%. ROC Vaspin-level curve has been performed for discriminating between mild to moderate and severe AV patients. Vaspin exhibited o.93o AUC. At a cut-off value of 3,911.5, sensitivity was 9%, the specificity was 9%, PPV was 81.8%, NPV was 94.7%, and accuracy was 9%. Conclusion: The level of Vaspin in the AV group was considerably greater than that of the control group with 96.7% susceptibility and 96.8% characteristics. Adipose and severity of AV were linked substantially with a greater vaspin level; the Vaspin level was proposed as a separate AV susceptibility and severity predictor.
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