O.M., A., I.A., S., M.A., E. (2022). Recent recommendations in Nutritional support to patients with sepsis in ICU. Benha Journal of Applied Sciences, 7(3), 23-29. doi: 10.21608/bjas.2022.244799
Abd El-Maqsoud O.M.; Shabob I.A.; El-Sayed M.A.. "Recent recommendations in Nutritional support to patients with sepsis in ICU". Benha Journal of Applied Sciences, 7, 3, 2022, 23-29. doi: 10.21608/bjas.2022.244799
O.M., A., I.A., S., M.A., E. (2022). 'Recent recommendations in Nutritional support to patients with sepsis in ICU', Benha Journal of Applied Sciences, 7(3), pp. 23-29. doi: 10.21608/bjas.2022.244799
O.M., A., I.A., S., M.A., E. Recent recommendations in Nutritional support to patients with sepsis in ICU. Benha Journal of Applied Sciences, 2022; 7(3): 23-29. doi: 10.21608/bjas.2022.244799
Recent recommendations in Nutritional support to patients with sepsis in ICU
Anesthesiology and critical care, Dept., Faculty of Medicine, Benha Univ., Benha, Egypt
Abstract
Despite recent advances in detection and treatment approaches, sepsis remains a significant cause of mortality globally. According to the Third International Agreement for Sepsis (Septic-3) consensus, the term "septic shock" is a subset of the more general term "sepsis" since it includes hypotension or an elevated lactate level despite attempts to revive the patient. Sepsis is caused by a variety of organisms, including Gram-positive and Gram-negative bacteria that produce toxins, an immune-compromised host, and maybe a genetic predisposition. When sepsis strikes, the body's response is immune-inflammatory, accompanied by the release of pro-inflammatory cytokines, which in turn triggers a neuro-endocrine cascade that leads to metabolic dysfunction and organ dysfunction. Cellular abnormalities such as mitochondrial damage and cytopathic hypoxia are also present. Taking 200 mg thiamine for a week post-ICU with high-dose short-term vitamin C and a 5-day Vitamin D supplementation for deficient individuals appears to be the most sensible course of action. It is a series of coordinated efforts used to establish the best kind, dosage and duration of nutrition treatment to achieve the highest therapeutic result, prevent side effects, and save costs. the following: Nutritional Stewardship and pharmaconutrition play a critical role in the treatment of sepsis, as well as the implementation of Nutritional Stewardship in the clinical context