Correlation between Vascular Endothelial cell Growth Factor (VEGF) and Muscular ultrasonography findings in Rheumatoid arthritis

M.E., Khalil; G.A., Hammad; A.Y., Alshambky; A.M., AL-Tabbakh; E.A., Youssef

doi:10.21608/bjas.2022.244929

Correlation between Vascular Endothelial cell Growth Factor (VEGF) and Muscular ultrasonography findings in Rheumatoid arthritis

Document Type : Original Research Papers

Authors

¹ Rheumatology, Rehabilitation and physical medicine, Dept.,Faculty of Medicine, Benha Univ., Benha, Egypt

² Medical Microbiology and Immunolog, Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

10.21608/bjas.2022.244929

Abstract

Background: Vascular endothelial growth factor (VEGF) is expressed in the joints of RA patients, it is synthesized and released by different cell types, such as subsynovial macrophages, fibroblasts surrounding microvessels, vascular smooth muscle cells and synovial lining cells. 30 patients with Rheumatoid arthritis were enrolled in our study, they were collected from the Rheumatology, Rehabilitation and Physical medicine outpatients' clinic and inpatients' department of Benha University Hospitals and 20 apparently healthy volunteers with a comparable age and sex of patients were included in the study as a control group.
Conclusion: Vascular endothelial growth factor concentrations were elevated in the sera of patients with RA and could be used as a marker for rheumatoid arthritis.

Keywords