The relation between abnormal yolk sac characteristics and miscarriage rate in first trimester of pregnancy

M.A., Mohamed; H.I., Mohamed; , I.S., Swedan; A.S., El-gohary

doi:10.21608/bjas.2022.244939

The relation between abnormal yolk sac characteristics and miscarriage rate in first trimester of pregnancy

Document Type : Original Research Papers

Authors

¹ M.B, B. Ch; 2010; Faculty of Medicine, Ain Shams Univ., Resident of obstetrics and Gynecology, Benha Teaching Hospital

² Obstetrics and Gynecology, Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

10.21608/bjas.2022.244939

Abstract

Background: The research included 200 pregnant women between the 7th and the 8th week of their pregnancy who were routinely seen at the hospital for prenatal follow-up visits. Participants were asked to recount their whole lives. Pregnant women were required to fill out a complete medical history form at their first visit at 5-7 weeks. There was a Case Recorded Form (CRF) for each participant, which was used to evaluate the YS features. First, individuals were asked whether they had had vaginal bleeding or other symptoms, and then YS features were checked again at 7 to 9 weeks (size, shape and echogenicity). This was the third and last appointment to the OB/GYN after 13 weeks of pregnancy. Pregnant women in their first trimester were the focus of this research, which assessed the accuracy of yolk sac features in predicting pregnancy outcomes. Methods: In March 2020, the research and ethical committee of the Faculty of Medicine approved the conduct of this prospective cohort study at Benha University Hospital. Between October 2020 and October 2021, the research team collected data on 200 pregnant women in their first trimester who went to the hospital for standard prenatal follow-up visits. Twenty women who refused to undergo transvaginal sonography testing were omitted from the study. Abortion rates increased significantly among women with abnormally big yolk sacs and abnormally tiny yolk sacs, but there was no statistically significant increase in abortion rates among women with abnormally small yolk sacs or abnormally shaped yolk sacs. YS diameter and echogenicity were found to be consistent with earlier investigations, although there was some disagreement about anomalous YS shape, which may be related to the small number of individuals with atypical yolk sac features. The present investigation found that instances with abnormally large yolk sacs and hyperechogenic centres had a statistically significant increase in the number of abortions. A substantial effect for the YS anomaly in the prediction of abortion was also shown in the current investigation. A big yolk and a hyperechogenic yolk sac are thus thought to be the most critical indicators for predicting early pregnancy loss among the yolk sac features. Additional research using a bigger sample size is required to assess the significance of the other criteria.

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