Demographic and clinical characteristics of patients with Helicobacter Pylori related dyspepsia

Balabel, M.M.; Metwally, M.A.; Elkholy, H.R; Kandil, A.I.

doi:10.21608/bjas.2022.254712

Demographic and clinical characteristics of patients with Helicobacter Pylori related dyspepsia

Document Type : Original Research Papers

Authors

¹ Hepatology and Gastroenterology, Shebin ElKom Teaching Hospital, MOHP, Egypt.

² Hepatology, Gastroenterology and Infectious Diseases Dept., Faculty of Medicine, Benha Univ., Benha, Egypt

10.21608/bjas.2022.254712

Abstract

Helicobacter pylori (H.pylori) is a common infection seen around the globe. Dyspepsia is a frequent symptom of H.
Pylori infection. Patients with dyspepsia caused by H.pylori were surveyed in this research to determine their demographic
and clinical features. From April 2019 to August 2020, researchers at Benha University Hospital and the department of
hepatology, gastroenterology, and infectious diseases performed this cross-sectional observational study on 200 adult
patients who had dyspepsia and were found to have H. pylori infection via an ELISA test for H. pylori stool ag. Males
comprised 43.5 percent of the patients with H.pylori dyspepsia in this study. One in four patients were smokers, and their
average age was 35.4 + 13.4 years, respectively, according to the study. There were 157 patients (78.5 percent) who
reported postprandial discomfort, 90 (45 percent) who reported heartburn, and 80 (40 percent) who reported bloating.
Baseline extra gastric symptoms were uncommon among these patients, with just a small percentage reporting them. In
contrast, just nine edema-sufferers (4.5 percent) were found among the 26 dyspnea sufferers (13 percent). There were 31
patients (15.5 percent) who had at least one prior surgery. Twenty-two patients (11 percent) had high blood pressure,
whereas fifteen patients (7.5 percent) had diabetes. Antibiotics were the most often reported prior medication use among
the patients, with a total of one hundred and twenty patients reporting such use (60 percent ). There were 39 patients
(19.5%) with a proven PPI medication history and 32 patients (16%) with NSAIDs, however. Postprandial epigastric
discomfort, heartburn, bloating, and nausea were the most common symptoms in H. pylori-associated dyspepsia. Antibiotic
usage in the past was present in more than half of the patients, raising the possibility that H. pylori resistance may be
impacted.

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