Afifi, W., Nawar, E., Ali, A., Abdel Haie, O., Elhady, A. (2023). Clinical, Neuroimaging and Electroencephalographic Characteristics of Pediatric Medically Intractable Epilepsy. Benha Journal of Applied Sciences, 8(1), 123-125. doi: 10.21608/bjas.2023.211164.1170
Wesam Elmenshawy Afifi; Elham Abdelghafar Nawar; Aziza Ibrahim Ali; Omima Mohamed Abdel Haie; Aliaa Mohamed Elhady. "Clinical, Neuroimaging and Electroencephalographic Characteristics of Pediatric Medically Intractable Epilepsy". Benha Journal of Applied Sciences, 8, 1, 2023, 123-125. doi: 10.21608/bjas.2023.211164.1170
Afifi, W., Nawar, E., Ali, A., Abdel Haie, O., Elhady, A. (2023). 'Clinical, Neuroimaging and Electroencephalographic Characteristics of Pediatric Medically Intractable Epilepsy', Benha Journal of Applied Sciences, 8(1), pp. 123-125. doi: 10.21608/bjas.2023.211164.1170
Afifi, W., Nawar, E., Ali, A., Abdel Haie, O., Elhady, A. Clinical, Neuroimaging and Electroencephalographic Characteristics of Pediatric Medically Intractable Epilepsy. Benha Journal of Applied Sciences, 2023; 8(1): 123-125. doi: 10.21608/bjas.2023.211164.1170
Clinical, Neuroimaging and Electroencephalographic Characteristics of Pediatric Medically Intractable Epilepsy
1Lecturer of Pediatrics Faculty of Medicine - Benha University
2Professor of Pediatrics Faculty of Medicine - Benha University
3Department of Pediatrics Faculty of Medicine - Benha University
4Assistant Professor of Pediatrics Faculty of Medicine - Benha University
Abstract
Objectives: to investigate the clinical, neuroimaging, and electroencephalographic characteristics of pediatric medically intractable epilepsy in order to predict and overcome this intractability. Methods: We conducted a prospective case-control study with 50 participants, divided into a study group of 25 patients with refractory epilepsy and a control group of 25 epileptic children with good control of seizures. All participants underwent a comprehensive assessment, including medical history, physical examination, neuroimaging, neurophysiological evaluation, and metabolic workup. Results: The study revealed that total number of patients was 50 (25 case 12 male & 13 female and 25 control 11 male & 14 female). Children with refractory epilepsy had abnormal neuroimaging. Additionally, the interictal EEG monitoring showed more frequent epileptiform discharges in the refractory group. Conclusions: It is important to evaluate pediatric patients with medically intractable epilepsy. Abnormal development, neuroimaging and frequent epileptiform discharges on EEG may indicate a higher likelihood of refractory epilepsy for further research with large number.