El-Sayed Akl, E., Farh, M., fouad, N., IBRAHIM, K. (2023). Growth Differentiation Factor-15 in psoriatic patients: a narrative review. Benha Journal of Applied Sciences, 8(6), 99-102. doi: 10.21608/bjas.2023.212060.1173
Essam El-Sayed Akl; Maram Farh; nehad fouad; karem IBRAHIM. "Growth Differentiation Factor-15 in psoriatic patients: a narrative review". Benha Journal of Applied Sciences, 8, 6, 2023, 99-102. doi: 10.21608/bjas.2023.212060.1173
El-Sayed Akl, E., Farh, M., fouad, N., IBRAHIM, K. (2023). 'Growth Differentiation Factor-15 in psoriatic patients: a narrative review', Benha Journal of Applied Sciences, 8(6), pp. 99-102. doi: 10.21608/bjas.2023.212060.1173
El-Sayed Akl, E., Farh, M., fouad, N., IBRAHIM, K. Growth Differentiation Factor-15 in psoriatic patients: a narrative review. Benha Journal of Applied Sciences, 2023; 8(6): 99-102. doi: 10.21608/bjas.2023.212060.1173
Growth Differentiation Factor-15 in psoriatic patients: a narrative review
Dermatology, Venereology and Andrology Dept., Faculty of Medicine, Benha University
Abstract
Background: Protein biomarkers in the bloodstream have the potential to aid in diagnosis, evaluate prognosis, and direct treatment. Multiple CV events have been linked to Growth Differentiation Factor 15, a cytokine released in response to cellular stress and inflammation. Psoriasis has been linked to cardiovascular disease, however the significance of this association is unclear. Objectives: Growth Differentiation Factor-15 (GDF-15) is being studied for its potential function in psoriasis. Data Sources: By searching and reviewing Medline databases (Pub Med and Medscape) and the role of GDF-15 in psoriasis available till 2022. Study Selection: The quality of each study was evaluated separately before inclusion. If they met any of the following criteria, we considered them for inclusion: 1. It is written and published in English. (2) Featured in reputable, academic publications. Third, explain why GDF-15 is so important for psoriasis sufferers..Data Extraction: There was a process of excluding studies that did not meet the inclusion criteria. Ethical permission, eligibility criteria, controls, information, and well-defined evaluation measures were all factors in determining the study's quality. Information relevant to our interested research outcomes was independently retrieved from each qualifying study utilising a data collecting form.Conclusions: We may infer that GDF-15's inflammatory actions may contribute to the aetiology and severity of psoriasis.