Evaluation of Galectin-3 level in Male Androgenetic Alopecia Patients

Document Type : Original Research Papers

Authors

1 Dermatology, Venereology and Andrology Dept., Faculty of Medicine, Benha University

2 Clinical and Chemical Pathology Dept., Faculty of Medicine, Benha University

Abstract

Background: Androgenetic Alopecia areata (AGA) is one of the most prevalent forms of hair loss, especially among men. Terminal hair transforms into intermediate hair and then vellus hair over time in people with AGA, a hereditary condition. Study participants and healthy volunteers will be compared for their blood levels of galectin-3.. Methods: This Sixty males with androgentic alopecia (age 18) and twenty and six age-matched healthy controls were studied in a case-control study. Serum galectin-3 levels were measured with other laboratory parameters in a thorough assessment of all patients. Results: The Patients and controls did not vary significantly in terms of age (P = 0.082), body mass index (BMI) (P = 0.478), or obesity (P = 0.517). Sixty percent of patients compared to twenty-five percent of controls smoked (P = 0.007). The median serum galectin-3 was substantially higher in patients than controls (20.38 ng/ml, 8.63 ng/ml respectively; P <0.001). A favourable association between serum galectin-3 and the course of the illness was found (r = 0.438, P 0.001) Conclusion: The The results of this investigation revealed that AGA patients, regardless of age or body mass index, had elevated blood galectin-3 levels.

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Benha Journal of Applied Sciences
Volume 8, Issue 11
November 2023
Pages 95-98

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