Assessment of Leptin Level in Serum of Patients with Seborrheic Dermatitis

Document Type : Original Research Papers

Authors

1 Dermatology, Venereolgoy and Andrology Department, Faculty of Medicine, Benha University

2 Clinical and Chemical Pathology Department, Faculty of Medicine, Benha University

Abstract

Background: Seborrheic dermatitis (SD) is a prevalent dermatological condition encountered in medical settings, known by various names such as sebo psoriasis, seborrheic eczema, and dandruff, among others. the rising prevalence of metabolic syndrome (MetS) poses a global health challenge, with emerging interest in its connection to various dermatological conditions, including SD, conditions like obesity are associated with increased leptin levels and resistance to its action, suggesting a complex interaction between leptin and skin health. Objective: This review aims to assess serum level of leptin in patients with SD and its relation to MetS in these patients, if any. Conclusions: patients with seborrheic dermatitis exhibit significantly higher serum leptin levels compared to healthy controls, indicating a potential role of leptin in the pathogenesis of the disease. Notably, serum leptin levels correlated with the severity of the disease and showed potential as a biomarker for disease severity.

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Benha Journal of Applied Sciences
Volume 9, Issue 2
February 2024
Pages 145-147

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