Salem, R., Abdel Khalik, G., Abdrabh, R., Taha, M. (2024). Beta 1 Integrin in Hair Follicles of Patients with Androgenetic Alopecia. Benha Journal of Applied Sciences, 9(6), 73-76. doi: 10.21608/bjas.2024.300703.1442
Rehab Salem; Ghada Mohamed Abdel Khalik; Rasha Mahmoud Abdrabh; Mervat Hesham Taha. "Beta 1 Integrin in Hair Follicles of Patients with Androgenetic Alopecia". Benha Journal of Applied Sciences, 9, 6, 2024, 73-76. doi: 10.21608/bjas.2024.300703.1442
Salem, R., Abdel Khalik, G., Abdrabh, R., Taha, M. (2024). 'Beta 1 Integrin in Hair Follicles of Patients with Androgenetic Alopecia', Benha Journal of Applied Sciences, 9(6), pp. 73-76. doi: 10.21608/bjas.2024.300703.1442
Salem, R., Abdel Khalik, G., Abdrabh, R., Taha, M. Beta 1 Integrin in Hair Follicles of Patients with Androgenetic Alopecia. Benha Journal of Applied Sciences, 2024; 9(6): 73-76. doi: 10.21608/bjas.2024.300703.1442
Beta 1 Integrin in Hair Follicles of Patients with Androgenetic Alopecia
1Assistant Professor of Dermatology, Venereology and Andrology Faculty of Medicine- Benha University
2Assistant Professor of Dermatology, Venereology and Andrology Faculty of Medicine - Benha University
3Assistant Professor of Pathology Faculty of Medicine- Benha University
4M.B.B. Ch
Faculty of Medicine – Benha University -2014
Abstract
Background: Androgenetic alopecia (AGA) is a hereditary hair loss illness characterized by a slow but steady transition from terminal to indeterminate and, eventually, vellus hairs. The process by which cells adhere to both the extracellular matrix and other cells is mediated by heterodimeric transmembrane proteins called integrins, which include of an α and a β component. The purpose of this paper is to examine the association between the severity of AGA etiopathogenesis and the tissue expression of β1 integrin, as well as to evaluate its participation in this process. Results: Beta 1 integrin has the potential to be an indicator of AGA severity and a key player in the disease's etiology. Background: Androgenetic alopecia (AGA) is a hereditary hair loss illness characterized by a slow but steady transition from terminal to indeterminate and, eventually, vellus hairs. The process by which cells adhere to both the extracellular matrix and other cells is mediated by heterodimeric transmembrane proteins called integrins, which include of an α and a β component. The purpose of this paper is to examine the association between the severity of AGA etiopathogenesis and the tissue expression of β1 integrin, as well as to evaluate its participation in this process. Results: Beta 1 integrin has the potential to be an indicator of AGA severity and a key player in the disease's etiology.
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