Androgеnеtic Alopеcia: A Comprеhеnsivе Rеviеw of Pathogеnеsis, Diagnosis, and Trеatmеnt Options

Hassan Sabry, Hanan; Adel Elfalah, Asmaa; Saleh  Metawalli Mohamed, Omnia; Ezzat Ibrahim, Samah

doi:10.21608/bjas.2024.319317.1498

Androgеnеtic Alopеcia: A Comprеhеnsivе Rеviеw of Pathogеnеsis, Diagnosis, and Trеatmеnt Options

Document Type : Review Articles

Authors

¹ Professor of Dermatology, Venereology and Andrology, Faculty of Medicine, Benha University, Egypt

² Assistant Professor of Clinical and Chemical Pathology, Faculty of Medicine, Benha University, Egypt

³ Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Zagazig University, Egypt

⁴ Lecturer of Dermatology, Venereology and Andrology, Faculty of Medicine, Benha University, Egypt

10.21608/bjas.2024.319317.1498

Abstract

Background: The most prevalent kind of male pattern baldness, androgenetic alopecia (AGA), has major emotional and social effects on affected individuals. The progressive miniaturisation of hair follicles is the outcome of a complex interaction between genetic predisposition and androgenic stimuli. Objеctivеs: The purpose of this review is to provide a thorough overview of AGA, including all aspects such as its clinical features, pathogenesis, diagnostic methods, and current treatment choices. Conclusions: AGA has several causes and progresses over time. Multiple diagnostic tests may corroborate a patient's symptoms and signs that point to a diagnosis. A variety of treatment methods were available, including surgical interventions, oral and topical therapies, and combination therapies, the latter of which showed encouraging results. The key to the best results is prompt intervention and ongoing treatment. New management avenues are opened up by emerging therapies such cell-based treatments and low-level laser therapy, although their long-term efficacy and safety need further research.

Keywords