The Role Of MicroRNAs In Psoriasis Vulgaris

Document Type : Original Research Papers

Authors

1 Professor of Dermatology, Venereology and Andrology Faculty of Medicine - Benha University

2 Assistant Professor of Dermatology, Venereology and Andrology Faculty of Medicine - Benha University

3 Assistant Professor of Clinical and Chemical Pathology Faculty of Medicine, Benha University

4 M.B.B.Ch. Faculty of Medicine, Benha University(2007)

Abstract

Psoriasis is a skin condition that arises from immune cell dysregulation, aberrant neovascularization, and atypical activation of . After transcription, tiny noncoding RNAs called microRNAs mostly influence gene expression. New research reveals that microRNAs are essential in the development of and that their expression is impaired in people with the condition. There is currently a lack of knowledge about the precise roles and action mechanisms of miR-193b in the development of psoriasis. Furthermore, factor and the STAT3 and NF-κB signaling pathways are both inhibited by miR-193b.Psoriasis is a skin condition that arises from immune cell dysregulation, aberrant neovascularization, and atypical activation of . After transcription, tiny noncoding RNAs called microRNAs mostly influence gene expression. New research reveals that microRNAs are essential in the development of and that their expression is impaired in people with the condition. There is currently a lack of knowledge about the precise roles and action mechanisms of miR-193b in the development of psoriasis. Furthermore, factor and the STAT3 and NF-κB signaling pathways are both inhibited by miR-193b.

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Benha Journal of Applied Sciences
Volume 9, Issue 10
October 2024
Pages 109-113

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