Screening of Von Willebrand Disease Among Children with Severe or Recurrent Attacks of Epistaxis.

Document Type : Original Research Papers

Authors

1 Professor of Pediatrics Faculty of Medicine-Benha University

2 Professor of Otorhinolaryngiology Faculty of Medicine-Benha University

3 Assistant Professor of Clinical and chemical pathology Faculty of Medicine-Benha University

4 Lecturer of Pediatrics Faculty of Medicine - Benha University

5 Department of Pediatrics Faculty of Medicine-Benha University

Abstract

Mild mucosal bleeding is the hallmark of von Willebrand disease (VWD), a congenital bleeding illness caused by a malfunction or deficit of von Willebrand factor (VWF). Von Willebrand disease is a prevalent but underappreciated bleeding ailment; our study's objective was to assess infants with severe or recurring epistaxis for the likelihood of this disorder. Methods and Patients: A total of seventy children who presented to the emergency room or outpatient clinic with epistaxis were included in this cross-sectional research. Complete blood counts, PTs, APTTs, VWF Ag, and VWF activities were among the blood assays performed on all patients in addition to clinical examinations and history gathering. One patient was found to have VWD out of seventy who presented with severe or recurring epistaxis over the course of the research. In conclusion, children experiencing severe or recurring epistaxis should be evaluated for VWD.

Topics: Epistaxis in Children with Von Willebrand Disease.

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Benha Journal of Applied Sciences
Volume 10, Issue 1 - Serial Number 1
Medical and Health Sciences:
January 2025
Pages 17-20

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