Anti-Mullerian Hormone (AMH) Variability in Cases of Polycystic Ovary Syndrome (PCOS) Phenotypes

Document Type : Original Research Papers

Authors

Obstetrics and Gynecology Department, Faculty of Medicine, Benha University, Benha, Egypt

Abstract

Background: Polycystic ovarian syndrome (PCOS) affects 8–13% of women and wreaks havoc on their hormones, metabolism, and mental wellbeing. The major goal of this research was to determine if anti-mullerian hormone (AMH) measurements in blood may be used to diagnose polycystic ovary syndrome (PCOS) and to predict its prognosis.
Methods: An obstetrician-gynecologist at Benha University Hospital and one hundred of her patients took part in the investigation. The patients were divided into two equal groups. Half of the women in Group I, which was called the PCOS group, were found to have PCOS according to the Rotterdam criteria. In Group II, fifty women were used as controls.
Results: Impressively, the AMH was able to predict PCOS with an 88% sensitivity and a 72% specificity.
Conclusions: Low AMH production was associated with polycystic ovary shape and PCOS ovulatory phenotypes, as shown in the study. The data provide support for the concept that AMH is crucial to the recognized mechanism of anovulation in polycystic ovary syndrome (PCOS). Our results suggest that measuring serum AMH might help in PCOS diagnosis and prognosis.

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Benha Journal of Applied Sciences
Volume 10, Issue 1 - Serial Number 1
Medical and Health Sciences:
January 2025
Pages 85-90

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