Short term outcome in patients presenting with acute coronary syndrome with left main coronary artery disease

Document Type : Review Articles

Authors

1 Professor of cardiology Faculty of medicine – Benha University

2 Assistant Professor of cardiovascular medicine Faculty of medicine- Benha University

3 Lecturer of cardiology Faculty of medicine – Benha University

4 Department cardiovascular medicine Faculty of medicine -Benha University

10.21608/bjas.2025.353008.1572

Abstract

Acute coronary syndrome (ACS) is a leading cause of mortality and is linked to negative outcomes. Patients with acute coronary syndrome (ACS) who also have left main (LM) disease may have a higher risk of complications and death. Despite considerable improvements in treatment methods, a small number of Patients still suffer from severe hemodynamic compromise and lethal arrhythmia as a result of left main ACS (LMACS). The obstructive left main (LM) coronary artery disease (occurs in about 6% of ACS Patients who undergo coronary angiography) supplies 75-100% of the left ventricular myocardium. Consequently, significant LM stenosis might lead to potentially fatal consequences. In Patients presenting with ST-elevation myocardial infarction (STEMI) requiring rapid revascularization (class IIa recommendation) or unstable angina/non -ST segment elevation myocardial in farction (UA/NSTEMI) who are not candidates for cor onary artery bypass grafting (CABG), current guidelines suggest percutaneous cor onary in tervention (PCI) for LM disease. Multivessel coronary artery disease is the most common cause of LM stenosis; yet, only 6-9% of individuals experience it as an isolated lesion. We want to assess the demographics, symptoms, and prognosis of Patients with ACS who receive LM-PCI in this concise study.

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