The Link between Acne Vulgaris and Metabolic Syndrome

Document Type : Original Research Papers

Authors

1 Dermatology, Venereology and Andrology Department, Faculty of Medicine, Benha University, Benha, Egypt

2 Clinical and Chemical Pathology Department, Faculty of Medicine, Benha University, Benha, Egypt

10.21608/bjas.2025.361469.1590

Abstract

Background: More than eighty percent of teenagers and young adults suffer with acne vulgaris, an inflammatory pilosebaceous illness. More and more research is focusing on the possible links between metabolic syndrome (MetS) and acne vulgaris. Objective: The purpose of this article is to provide a synopsis of the research on the association between metabolic syndrome, acne vulgaris, and the severity of acne. Data Sources: A search of the Medline databases (Pub Med and Medscape) was conducted to gather literature on the origins, pathophysiology, clinical images, and the function of metabolic syndrome in patients with acne vulgaris. The literature also discusses the association between metabolic syndrome and the severe decrease of the illness up to 2024. Data Extraction: Research was not considered for inclusion if it did not meet certain requirements. Ethical permission, clear eligibility criteria, suitable controls, sufficient information, and well-defined evaluation measures were all variables in determining the study's quality. We used a data collecting form to independently extract information relevant to our research results from all qualifying studies. Conclusions: Hormonal shifts, insulin resistance, oxidative stress, and persistent inflammation are shared features of both MetS and acne vulgaris. Severe acne is more common in those with MetS, according to studies.

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