Berbesh, S. (2023). AMELIORATIVE EFFECT OF SPIRULINA PLATENSIS AGAINST LEAD TOXICITY IN BROILER CHICKENS.. Benha Journal of Applied Sciences, (), -. doi: 10.21608/bjas.2023.106499.1005
Sara A Berbesh. "AMELIORATIVE EFFECT OF SPIRULINA PLATENSIS AGAINST LEAD TOXICITY IN BROILER CHICKENS.". Benha Journal of Applied Sciences, , , 2023, -. doi: 10.21608/bjas.2023.106499.1005
Berbesh, S. (2023). 'AMELIORATIVE EFFECT OF SPIRULINA PLATENSIS AGAINST LEAD TOXICITY IN BROILER CHICKENS.', Benha Journal of Applied Sciences, (), pp. -. doi: 10.21608/bjas.2023.106499.1005
Berbesh, S. AMELIORATIVE EFFECT OF SPIRULINA PLATENSIS AGAINST LEAD TOXICITY IN BROILER CHICKENS.. Benha Journal of Applied Sciences, 2023; (): -. doi: 10.21608/bjas.2023.106499.1005
AMELIORATIVE EFFECT OF SPIRULINA PLATENSIS AGAINST LEAD TOXICITY IN BROILER CHICKENS.
Articles in Press, Accepted Manuscript, Available Online from 20 February 2023
Fronsic medicine and toxicology, faculty of veterinary medicine, Benha university, Benha, Egypt.
Abstract
Backgroud: Lead acetate (Pb) is an oldest and widespread environmental toxicant that led to cumulative injury in humans and all living organisms .Spirulina platensis (SP) is a cyanobacteria with strong antioxidant, anti-inflammatory, hepatoprotective, nephroprotective, growth, productive and reproductive enhancer of animal and poultry. Objective is to investigate the ameliorative effect of Spirulina platensis (SP) against lead induced oxidative damage in broiler chickens. Method : (60) broiler Chicks divided randomly into four equal groups (15 Each).Group 1 act as control given distalled water orally, group 2 given distalled water orally and 3g/kg of diet of SP ,group 3 given 160mg/kg B.wt of Lead acetate, group 4 given 160mg/kg B.wt of lead acetate and 3g/kg diet of SP . Results: significant improvement in some of growth parameters like final body weight in chicks treated with SP and as result significant decrease in FCR. However, a significant decrease in liver function, renal parameters, total Pb residues in muscles, livers and kidneys , oxidative parameters malondialdehyde (MDA), while Superoxide disuutase (SOD) and total antioxidant capacity (TAC) ) show significant increase in there levels. Pathologic analysis of liver and kidneys revealed severe degenerative and necrotic changes in Pb- exposed chicks, which was-ameliorated by supplementation of SP.