Melasma: Background, pathogenesis, diagnosis and treatment lines

Document Type : Review Articles

Authors

1 Professor of Dermatology, Venereology and Andrology, Faculty of Medicine, Benha University, Egypt

2 Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Benha University, Egypt

3 Lecturer of Dermatology, Venereology and Andrology, Faculty of Medicine, Benha University, Egypt

Abstract

Background: Melasma, symmetrical brown macules in sunlight-exposed regions, is a common acquired condition. Several treatments have mixed effectiveness and tolerance. Objective: This page discusses melasma epidemiology, clinical features, diagnosis, and therapy. Melasma aetiology, pathophysiology, clinical images, and decrease up to 2024 were found in Medline databases (Pub Med and Medscape). One year after giving birth, pregnancy-related melasma generally disappears with treatment. Six percent spontaneous remission. About 30% of individuals have pigmentary consequences. Oral contraceptive users and those with darker pigmented melasma have higher persistence. Pregnant women having a history of several pregnancies are more likely to have melasma for the first time Melasma, a common skin ailment, causes dark spots. It is more prevalent in childbearing women and symmetrical the illness reports were mostly female, with an estimated ratio of 9 or 10 females to 1 man. Melasma is more common in pregnant women, supporting its hormonal cause. High oestrogen, progesterone, and melanocortin levels during pregnancy. studies that did not meet inclusion requirements were excluded. Ethical approval, eligibility criteria, controls, information, and evaluation measures were study quality assessment factors. A data collecting form was used to independently extract data from each qualifying research for our study results.

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